Zeiss recently announced the new Otus 100mm f/1.4 prime lens for Canon and Nikon full-frame DSLRs. In some ways I don't see the point. Pretty much every 100mm, 105mm, 135mm lens by any of the major brands have high resolution and produce extraordinarily sharp images. The major selling point for this lens appears to be the elimination of color fringing. At $4,500 USD I think I can live with what I have. But I suppose that if color fringing is a bugaboo for you and you have a lot of loose change in your pockets, then it may be just the lens you've been looking for. Of course, it is manual focus.